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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCPEP1
All Species:
21.82
Human Site:
S404
Identified Species:
32
UniProt:
Q9HB40
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB40
NP_067639.1
452
50831
S404
L
K
W
K
A
L
Y
S
D
P
K
S
L
E
T
Chimpanzee
Pan troglodytes
XP_001172174
452
50766
S404
L
K
W
K
A
L
Y
S
D
P
K
S
L
E
T
Rhesus Macaque
Macaca mulatta
XP_001104815
452
50613
S404
L
K
W
K
A
L
H
S
D
P
K
S
L
E
T
Dog
Lupus familis
XP_537688
477
53125
S429
L
K
W
K
A
L
Y
S
D
P
K
S
S
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q920A5
452
50948
T404
L
K
W
K
A
L
Y
T
D
P
K
S
S
E
T
Rat
Rattus norvegicus
Q920A6
452
51156
T404
L
K
W
K
A
L
Y
T
N
P
K
S
S
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521733
560
62210
N510
L
K
W
K
A
L
Y
N
D
P
K
R
W
E
T
Chicken
Gallus gallus
NP_001012821
446
49959
V390
Q
R
W
K
A
L
Y
V
S
P
E
S
T
D
T
Frog
Xenopus laevis
NP_001088737
443
49367
E393
L
K
W
T
A
L
R
E
G
Q
E
S
L
E
T
Zebra Danio
Brachydanio rerio
NP_956486
445
49600
D397
L
K
W
T
A
L
E
D
P
Q
E
Q
S
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392686
435
48876
P388
W
H
Y
S
P
R
Y
P
I
V
V
Q
E
I
I
Nematode Worm
Caenorhab. elegans
NP_872130
445
50095
F395
N
S
T
T
R
H
S
F
K
T
Q
S
F
P
L
Sea Urchin
Strong. purpuratus
XP_785691
470
52220
V420
T
T
W
T
P
E
Y
V
K
S
K
Q
G
D
T
Poplar Tree
Populus trichocarpa
XP_002313552
489
53783
C419
M
N
R
T
P
L
L
C
G
A
E
G
Q
L
T
Maize
Zea mays
NP_001148149
464
50034
D414
P
R
T
P
I
Y
C
D
K
E
G
Q
S
G
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q67Y83
461
51734
F411
K
M
E
R
E
P
L
F
C
E
S
D
R
A
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96
82.8
N.A.
82
82.7
N.A.
60.7
65.9
65.9
62.8
N.A.
N.A.
42
41.8
47.8
Protein Similarity:
100
99.3
99.1
88.2
N.A.
90.7
91.8
N.A.
70.7
78.9
77.2
77.6
N.A.
N.A.
59.2
58.6
63.6
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
80
N.A.
80
53.3
60
40
N.A.
N.A.
6.6
6.6
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
73.3
66.6
53.3
N.A.
N.A.
13.3
13.3
33.3
Percent
Protein Identity:
42.7
45
N.A.
42.9
N.A.
N.A.
Protein Similarity:
57.2
58.6
N.A.
60.7
N.A.
N.A.
P-Site Identity:
13.3
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
63
0
0
0
0
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
7
7
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
13
38
0
0
7
0
13
0
% D
% Glu:
0
0
7
0
7
7
7
7
0
13
25
0
7
50
0
% E
% Phe:
0
0
0
0
0
0
0
13
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
13
0
7
7
7
7
0
% G
% His:
0
7
0
0
0
7
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
7
0
0
0
0
7
7
% I
% Lys:
7
57
0
50
0
0
0
0
19
0
50
0
0
0
0
% K
% Leu:
57
0
0
0
0
69
13
0
0
0
0
0
25
7
7
% L
% Met:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
7
7
0
0
0
0
0
0
% N
% Pro:
7
0
0
7
19
7
0
7
7
50
0
0
0
7
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
13
7
25
7
7
0
% Q
% Arg:
0
13
7
7
7
7
7
0
0
0
0
7
7
0
0
% R
% Ser:
0
7
0
7
0
0
7
25
7
7
7
57
32
0
0
% S
% Thr:
7
7
13
32
0
0
0
13
0
7
0
0
7
0
88
% T
% Val:
0
0
0
0
0
0
0
13
0
7
7
0
0
0
0
% V
% Trp:
7
0
69
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
7
0
0
7
57
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _